https://ucl-pharmacometrics.r-universe.devRecent package updates in ucl-pharmacometricsR-universehttps://github.com/ucl-pharmacometrics.pnghttps://ucl-pharmacometrics.r-universe.devMon, 08 Jun 2026 00:43:52 GMThuangzhonghui22@gmail.com (Zhonghui Huang)Provides automated methods for generating initial parameter estimates in population pharmacokinetic modeling. The pipeline integrates adaptive single-point methods, naive pooled graphic approaches, noncompartmental analysis methods, and parameter sweeping across pharmacokinetic models. It estimates residual unexplained variability using either data-driven or fixed-fraction approaches and assigns pragmatic initial values for inter-individual variability. These strategies are designed to improve model robustness and convergence in 'nlmixr2' workflows. For more details see Huang Z, Fidler M, Lan M, Cheng IL, Kloprogge F, Standing JF (2025) <doi:10.1007/s10928-025-10000-z>.https://github.com/r-universe/ucl-pharmacometrics/actions/runs/27117877264Mon, 08 Jun 2026 00:43:52 GMTnlmixr2autoinit1.0.1successhttps://ucl-pharmacometrics.r-universe.devhttps://github.com/ucl-pharmacometrics/nlmixr2autoinitworkflow_nlmixr2.Rmdworkflow_nlmixr2.htmlIntegration with nlmixr22026-05-06 21:08:452026-05-06 21:08:45workflow_nlmixr2auto.Rmdworkflow_nlmixr2auto.htmlIntegration with nlmixr2auto2026-05-06 21:08:452026-05-06 22:31:17parameter_sweeping.Rmdparameter_sweeping.htmlParameter Sweeping and Visualisation2026-05-06 21:08:452026-05-06 21:08:45running_nlmixr2autoinit.Rmdrunning_nlmixr2autoinit.htmlRunning nlmixr2autoinit2026-05-06 21:08:452026-05-07 08:44:11huangzhonghui22@gmail.com (Zhonghui Huang)Automated population pharmacokinetic modeling framework for data-driven initialisation, model evaluation, and metaheuristic optimization. Supports genetic algorithms, ant colony optimization, tabu search, and stepwise procedures for automated model selection and parameter estimation within the nlmixr2 ecosystem.https://github.com/r-universe/ucl-pharmacometrics/actions/runs/27105390593Wed, 18 Feb 2026 19:23:06 GMTnlmixr2auto1.0.0successhttps://ucl-pharmacometrics.r-universe.devhttps://github.com/ucl-pharmacometrics/nlmixr2auto